DNannotator ["dE-"en-'A-no-"tAtor]: Tools for batch and custom annotation of regional genomic sequences

Human data (Genome, Gene, and SNP) only!

Some tools will work for studies of the other species, if you do not need to use data provided by our systems, including genome sequence, SNPs, etc.

Terms used by DNannotator

Annotation:  Used in its narrow sense meaning mapping of features to genomic DNA sequences.

Customized:  Users supply their own annotation source data, such as SNPs, genes, STSs, oligos etc., and their preferred target gDNA sequence for annotation.

High Throughput: Maps batches of source data (prepared by users) onto one gDNA sequence.

Genomic region: A genomic region sized < ~ 30 Mb.  DNannotator is a supplement to public annotation efforts such as NCBI's Map Viewer, UCSC's Genome Browser or Sanger's Ensembl.   The user can merge annotation from all sources of public annotation, and from his own findings, onto the genomic region of interest.


New User:  Readme First

Return User: Fast Track


All pages were tested only for Netscape 7, IE 6.

Bug Report                                    Other Suggestions


Please cite the references:

  1. Chunyu Liu, Tu Nguyen, Ruifang Zhang, Fengxia Yao, Zanhua Zhu, Elliot S. Gershon. SNP Information Mining Pipeline (SIMP) for Complex Disease Studies. 53rd Annual Meeting of the American Society of Human Genetics.  Los Angeles, CA, 4-8, November. Am J Human Genet 73(5):421. abstract# 1470.

  2. Chunyu Liu, Tom I. Bonner, Tu Nguyen, Jennifer L. Lyons, Susan L. Christian, Elliot S. Gershon. DNannotator: annotation software tool kit for regional genomic sequences. Nucleic Acids Res. 2003. 31(13):3729-3735

  3. Tu Nguyen, Chunyu Liu, Elliot S. Gershon, Francis J. McMahon. Frequency Finder: A multi-source web application for collection of public allele frequencies of SNP markers. Bioinformatics. 2003 (in press)

Copyright © 2001 University of Chicago, All rights reserved.
System developer: Chunyu LiuYuanwen LiuTu Nguyen    English Consultant: Jennifer Lyons.

11/12/2003 updated